TOPMed CORE 2.0
NHLBI Trans-Omics for Precision Medicine – Centralized Omics REsource (CORE) 2.0
HHS IDIQ Active - Obligated to date
- $93.3M
- Task orders
- 15
- Contractors
- 9
- Ceiling
- ~$73 million
Vehicle overview
The NHLBI Trans-Omics for Precision Medicine (TOPMed) Centralized Omics Resource (CORE) 2.0 is an IDIQ contract managed by the National Heart, Lung, and Blood Institute of the NIH. It provides large-scale genomic data resources and omics measurements to support precision medicine research. The vehicle is valued at approximately $73 million over a five-year period.
The contract covers whole genome sequencing and omics measures including DNA methylation, RNA expression patterns, and metabolic data. It supports researchers studying heart, lung, blood, and sleep disorders.
Vehicle details
- Ordering period
-
5-year period of performance with a 4.5-year ordering period
- Ceiling
-
~$73 million
Where agencies spend through TOPMed CORE 2.0
See which agencies and types of work reported the most positive obligations through TOPMed CORE 2.0 in the last 12 months.
-
Department of Health and Human Services
- Last 12mo obligations
- $17.7M
- Last 12mo awards
- 5
Coverage period Jul 28, 2025–Jul 27, 2026
TOPMed CORE 2.0 contract holders
| Contractor | Obligated | Task orders |
|---|---|---|
| BAYLOR COLLEGE OF MEDICINE | $38.4M | 3 |
| THE BROAD INSTITUTE, INC | $32.9M | 3 |
| UNIVERSITY OF WASHINGTON | $8.9M | 3 |
| NEW YORK GENOME CENTER, INC. | $8.3M | 3 |
| THE LELAND STANFORD JUNIOR UNIVERSITY | $4.7M | 2 |
| PSOMAGEN INC | $72.6K | 1 |
| CEDARS-SINAI MEDICAL CENTER | $0 | 0 |
| UNIVERSITY OF CALIFORNIA SAN DIEGO | $0 | 0 |
| VANDERBILT UNIVERSITY MEDICAL CENTER | $0 | 0 |
NAICS coverage
Frequently asked questions
- What is TOPMed CORE 2.0?
- The NHLBI Trans-Omics for Precision Medicine (TOPMed) Centralized Omics Resource (CORE) 2.0 is an IDIQ contract managed by the National Heart, Lung, and Blood Institute of the NIH. It provides large-scale genomic data resources and omics measurements to support precision medicine research. The vehicle is valued at approximately $73 million over a five-year period.
- Which agency manages TOPMed CORE 2.0?
- NHLBI Trans-Omics for Precision Medicine – Centralized Omics REsource (CORE) 2.0 is a IDIQ managed by Department of Health and Human Services.
- What can agencies acquire through TOPMed CORE 2.0?
- The contract covers whole genome sequencing and omics measures including DNA methylation, RNA expression patterns, and metabolic data. It supports researchers studying heart, lung, blood, and sleep disorders.
- How much has been obligated through TOPMed CORE 2.0?
- $93.3M has been obligated across 15 task orders.
- Which agencies use TOPMed CORE 2.0?
- In the 12 months ending July 27, 2026, agencies with reported awards through TOPMed CORE 2.0 included the Department of Health and Human Services. The Department of Health and Human Services reported $17.7M in positive obligations for Testing Laboratories and Services (NAICS 541380). Figures use reported USAspending award data.
- How many contractors hold TOPMed CORE 2.0?
- 9 contractors hold a position on TOPMed CORE 2.0.
- What is the contract ceiling of TOPMed CORE 2.0?
- TOPMed CORE 2.0 has a program ceiling of ~$73 million.
- Is TOPMed CORE 2.0 active?
- Yes, TOPMed CORE 2.0 is currently active (ordering period: 5-year period of performance with a 4.5-year ordering period).
Track the contracts behind TOPMed CORE 2.0
Sweetspot helps capture teams monitor awards, incumbents, recompetes, and agency demand across federal contract vehicles.
Schedule a Demo