Federal Capture Intelligence

Top HHS biological product (except diagnostic) manufacturing contractors (NAICS 325414)

Contract actions: October 1, 2021 – September 10, 2026 Updated September 11, 2026 Department of Health and Human Services agency guide NAICS 325414 · Biological Product (except Diagnostic) Manufacturing
Latest 12 months
$303.0M
Net obligations · Down $3.0M vs. $306.0M preceding
Prime contractors
43
With positive obligations in the latest 12 months

Research the HHS federal contracting market for biological product (except diagnostic) manufacturing under NAICS 325414. Compare top federal contractors and market share, reported contract obligations and spending trends, funding-office attribution, recent award activity, contract types, competition, and procurement methods, and potential recompete research leads.

Contract obligation trends for Biological Product (except Diagnostic) Manufacturing at the Department of Health and Human Services

Federal records show $1.7B in net obligations across 1,934 awards in Biological Product (except Diagnostic) Manufacturing at the Department of Health and Human Services from Oct 1, 2021 through Sep 10, 2026. This market accounts for 1.2% of $145.5B in agency-wide net prime contract obligations over the period shown. Latest 12-month net obligations decreased 1.0% from $306.0M to $303.0M. 2 prime contractors accounted for at least 80% of positive obligations in that latest period.

Fiscal-year activity

FY26 is year-to-date through Sep 10, 2026; earlier years show complete fiscal-year totals.

FY26 year-to-date: $302.6M versus −$120.4M through the same date in FY25 (Not comparable).
Net obligations · complete fiscal yearNet obligations · FY26 YTDContract actions
View fiscal-year data table
Fiscal yearNet obligationsContract actionsCoverage
FY2022$386.9M805Complete
FY2023$199.4M622Complete
FY2024$911.6M571Complete
FY2025−$120.0M319Complete
FY2026$302.6M161YTD through Sep 10, 2026

Market at a glance

All reported prime contract awards
All-period net obligations
$1.7B
1,934 awards · 347 prime contractors
Latest 12-month movement
−1.0%
$303.0M vs. $306.0M
Leading eight prime share
99.0%
Share held by the eight leading prime contractors in the latest 12 months
View agency share, denominators, and set-aside reporting
Agency context
1.2% of $145.5B in agency-wide net obligations.
Set-aside share when reported
7.6% of 1,746 awards with reported set-aside status.
Set-aside reporting
133 set aside · 1,613 no set-aside · 188 not reported

What changed in the last 12 months?

Sep 11, 2025–Sep 10, 2026, compared with Sep 11, 2024–Sep 10, 2025.

Competitive shifts

ADVANCED TECHNOLOGY INTERNATIONAL had the largest decline in reported obligations
$339.5M→$225.0M−$114.5M
The contractor now ranks #1 by positive obligations and accounts for 73.5% of positive obligations, based on 20 reported actions.

Award activity

Buyer demand

Reported obligations through NATIONAL INSTITUTES OF HEALTH NIAID decreased
$3.9M→$471K−$3.4M
Latest-period activity spans 32 awards across 24 prime contractors.
How these findings are calculated

Findings are selected from matched-period changes in obligations, share, rank, funding offices, concentration, reported set-asides, material award actions, and agency-peer outliers. Related signals are combined, and only material evidence-backed changes are shown. Review the full methodology.

Federal contract obligations by funding office

See how positive obligations were attributed across funding offices in the 12 months ending Sep 10, 2026.

81.0% of positive obligations were attributed to OFC ASST SEC FOR PREPARENESS RES. That represents $251.6M, up $332.4M from the preceding 12 months.

Latest 12-month share of positive obligations; the gray segment represents all other reported offices.

  1. OFC ASST SEC FOR PREPARENESS RES81.0% · $251.6M · up $332.4M
  2. ASPR/ORM-SNS17.0% · $52.8M · down $3.0M
  3. NATIONAL INSTITUTES OF HEALTH OLAO0.71% · $2.2M · up $2.2M
  4. NATIONAL INSTITUTES OF HEALTH NHGRI0.24% · $732K · up $640K
  5. NATIONAL INSTITUTES OF HEALTH NHLBI0.21% · $653K · down $249K
  6. All other reported offices0.87% of positive obligations
View reported office rankings, comparisons, and evidence

USAspending assigns each award to a funding office. That office may differ from the requiring activity, program office, contracting office, individual buyer, or actual customer.

  1. Reported funding office

    OFC ASST SEC FOR PREPARENESS RES

    #1New to the positive-obligation ranking

    Latest 12 months

    $251.6M

    81.0% of positive obligations

    Versus preceding 12 months

    +$332.4M

    2 active prime contractors · 6 awards

    View office comparison and evidence

    Reported obligations moved from $80.8M in net deobligations to $251.6M in net obligations. The office’s share of positive obligations moved from 0% to 81.0%, a change of +81.0 percentage points.

    The latest period contains 10 actions across 6 awards and 1 newly active prime contractor. The preceding period contained 4 active prime contractors and 5 awards.

    Leading award-level changes

  2. Reported funding office

    ASPR/ORM-SNS

    #2Rank unchanged

    Latest 12 months

    $52.8M

    17.0% of positive obligations

    Versus preceding 12 months

    −$3.0M

    1 active prime contractor · 1 award

    View office comparison and evidence

    Reported obligations decreased 5.3% from $55.7M to $52.8M. The office’s share of positive obligations moved from 14.3% to 17.0%, a change of +2.7 percentage points.

    The latest period contains 1 action across 1 award. The preceding period contained 1 active prime contractor and 1 award.

  3. Reported funding office

    NATIONAL INSTITUTES OF HEALTH OLAO

    #3New to the positive-obligation ranking

    Latest 12 months

    $2.2M

    0.71% of positive obligations

    Versus preceding 12 months

    +$2.2M

    5 active prime contractors · 5 awards

    View office comparison and evidence

    Reported obligations moved from $10K in net deobligations to $2.2M in net obligations. The office’s share of positive obligations moved from 0% to 0.71%, a change of +0.7 percentage points.

    The latest period contains 7 actions across 5 awards and 5 newly active prime contractors. The preceding period contained 3 active prime contractors and 5 awards.

  4. Reported funding office

    NATIONAL INSTITUTES OF HEALTH NHGRI

    #4Up 10 from #14

    Latest 12 months

    $732K

    0.24% of positive obligations

    Versus preceding 12 months

    +$640K

    5 active prime contractors · 5 awards

    View office comparison and evidence

    Reported obligations increased 697.6% from $92K to $732K. The office’s share of positive obligations moved from 0.020% to 0.24%, a change of +0.2 percentage points.

    The latest period contains 5 actions across 5 awards and 4 newly active prime contractors. The preceding period contained 3 active prime contractors and 7 awards.

  5. Reported funding office

    NATIONAL INSTITUTES OF HEALTH NHLBI

    #5Up 4 from #9

    Latest 12 months

    $653K

    0.21% of positive obligations

    Versus preceding 12 months

    −$249K

    7 active prime contractors · 8 awards

    View office comparison and evidence

    Reported obligations decreased 27.6% from $902K to $653K. The office’s share of positive obligations moved from 0.23% to 0.21%, a change of 0.0 percentage points.

    The latest period contains 8 actions across 8 awards and 3 newly active prime contractors. The preceding period contained 19 active prime contractors and 38 awards.

  6. Reported funding office

    NATIONAL INSTITUTES OF HEALTH NIAID

    #6Down 2 from #4

    Latest 12 months

    $471K

    0.15% of positive obligations

    Versus preceding 12 months

    −$3.4M

    24 active prime contractors · 32 awards

    View office comparison and evidence

    Reported obligations decreased 87.9% from $3.9M to $471K. The office’s share of positive obligations moved from 1.0% to 0.15%, a change of −0.8 percentage points.

    The latest period contains 33 actions across 32 awards and 12 newly active prime contractors. The preceding period contained 36 active prime contractors and 59 awards.

  7. Reported funding office

    NATIONAL INSTITUTES OF HEALTH - CC

    #7Rank unchanged

    Latest 12 months

    $393K

    0.13% of positive obligations

    Versus preceding 12 months

    −$725K

    17 active prime contractors · 19 awards

    View office comparison and evidence

    Reported obligations decreased 64.8% from $1.1M to $393K. The office’s share of positive obligations moved from 0.29% to 0.13%, a change of −0.2 percentage points.

    The latest period contains 20 actions across 19 awards and 9 newly active prime contractors. The preceding period contained 28 active prime contractors and 54 awards.

  8. Reported funding office

    FDA OFFICE OF ACQ GRANT SVCS

    #8Up 3 from #11

    Latest 12 months

    $355K

    0.11% of positive obligations

    Versus preceding 12 months

    −$35K

    9 active prime contractors · 10 awards

    View office comparison and evidence

    Reported obligations decreased 8.9% from $390K to $355K. The office’s share of positive obligations moved from 0.10% to 0.11%, a change of 0.0 percentage points.

    The latest period contains 10 actions across 10 awards and 7 newly active prime contractors. The preceding period contained 4 active prime contractors and 8 awards.

  9. Reported funding office

    NATIONAL INSTITUTES OF HEALTH NIA

    #9Down 4 from #5

    Latest 12 months

    $323K

    0.10% of positive obligations

    Versus preceding 12 months

    −$1.3M

    6 active prime contractors · 7 awards

    View office comparison and evidence

    Reported obligations decreased 80.0% from $1.6M to $323K. The office’s share of positive obligations moved from 0.41% to 0.10%, a change of −0.3 percentage points.

    The latest period contains 7 actions across 7 awards and 4 newly active prime contractors. The preceding period contained 7 active prime contractors and 7 awards.

  10. Reported funding office

    NATIONAL INSTITUTES OF HEALTH NINDS

    #10Up 8 from #18

    Latest 12 months

    $299K

    0.10% of positive obligations

    Versus preceding 12 months

    +$281K

    2 active prime contractors · 2 awards

    View office comparison and evidence

    Reported obligations increased 1565.3% from $18K to $299K. The office’s share of positive obligations moved from 0% to 0.10%, a change of +0.1 percentage points.

    The latest period contains 2 actions across 2 awards and 2 newly active prime contractors. The preceding period contained 1 active prime contractor and 1 award.

  11. Reported funding office

    INDUSTRIAL BASED MANUFACTURING AND SUPPLY CHAIN (IBMSC)

    No positive-obligation rank

    Latest 12 months

    $0

    0% of positive obligations

    Versus preceding 12 months

    −$309.5M

    1 active prime contractor · 1 award

    View office comparison and evidence

    Reported obligations decreased 100.0% from $309.5M to $0. The office’s share of positive obligations moved from 79.1% to 0%, a change of −79.1 percentage points.

    The latest period contains 1 action across 1 award. The preceding period contained 1 active prime contractor and 4 awards.

    Leading award-level changes

  12. Reported funding office

    ASPR BARDA DIV CONTRACTS MGMT & ACQ

    No positive-obligation rank

    Latest 12 months

    $0

    0% of positive obligations

    Versus preceding 12 months

    +$4.2M

    0 active prime contractors · 0 awards

    View office comparison and evidence

    Reported obligations moved from $4.2M in net deobligations to $0 in net obligations. The office’s share of positive obligations moved from 0% to 0%, a change of 0.0 percentage points.

    The latest period contains 0 actions across 0 awards. The preceding period contained 2 active prime contractors and 2 awards.

  13. Reported funding office

    BARDA - ASPR / DAAPPO / BARDA DCMA

    No positive-obligation rank

    Latest 12 months

    −$7.6M

    0% of positive obligations

    Versus preceding 12 months

    −$22.1M

    8 active prime contractors · 19 awards

    View office comparison and evidence

    Reported obligations moved from $14.5M in net obligations to $7.6M in net deobligations. The office’s share of positive obligations moved from 3.7% to 0%, a change of −3.7 percentage points.

    The latest period contains 29 actions across 19 awards and 3 newly active prime contractors. The preceding period contained 10 active prime contractors and 37 awards.

Contract types, competition, and procurement methods

From Sep 11, 2025 through Sep 10, 2026, 63 awards had positive obligations totaling $320.9M. Negotiated Proposal/Quote was the leading reported procedure, accounting for 89.5% of positive obligations. Awards with a reported parent IDV accounted for 73.8%.

Leading award type
73.8%
Delivery Order
Leading reported procedure
89.5%
Negotiated Proposal/Quote
Reported parent IDV
73.8%
of positive obligations had a reported parent IDV
Median reported offers
1
54 of 63 awards reported offers

Buying method changes

Compared with Sep 11, 2024–Sep 10, 2025. Based on 63 current awards and 204 preceding awards with positive net obligations.

Median positive award obligations
$51K
Up from $23K in the preceding period
How to read these changes

Directional color and the Up or Down labels show historical movement only. Green does not mean favorable and red does not mean unfavorable; neither predicts a future procurement method.

Same-NAICS comparison

Compared with the NAICS 325414 peer median, parent-IDV obligation share is 25.8 percentage points lower, reported full-and-open obligation share is 64.2 percentage points higher, delivery-order obligation share is 25.7 percentage points lower, and median positive award obligations are 45.6% lower.

MeasureThis marketPeer medianDifference
Parent-IDV obligation share73.8%99.6%-25.8 pts
Reported full-and-open obligation share89.5%25.4%+64.2 pts
Delivery-order obligation share73.8%99.5%-25.7 pts
Median positive award obligations$51K$93K-45.6%
Peer cohort and comparison limits

The peer median gives each of the 3 eligible agency markets equal weight. The included agency markets are:

Agency mission, scale, and acquisition context can differ. Peer position does not establish market attractiveness or predict a future procurement method.

View buying-method details and data coverage

Award types

Reported valueAwardsPositive obligationsShare
Delivery Order(C)9$236.8M73.8%
Definitive Contract(D)4$79.6M24.8%
Purchase Order(B)49$4.5M1.4%
BPA Call(A)1$11K0%

Reported parent-award types

Reported valueAwardsPositive obligationsShare
IDC(B)9$236.8M73.8%
BPA(E)1$11K0%
Not reported53$84.1M26.2%

Single- or multiple-award parent structure

Reported valueAwardsPositive obligationsShare
Single Award(S)10$236.8M73.8%
Not reported53$84.1M26.2%

Solicitation procedures

Reported valueAwardsPositive obligationsShare
Negotiated Proposal/Quote(NP)6$287.4M89.5%
Only One Source(SSS)9$27.4M8.5%
Simplified Acquisition(SP1)34$5.5M1.7%
Sp1(SIMPLIFIED ACQUISITION)12$678K0.21%
Sss(ONLY ONE SOURCE)2$27K0.010%

Extent competed

Reported valueAwardsPositive obligationsShare
Full and Open Competition(A)6$287.4M89.5%
Not Competed(C)9$27.4M8.5%
Not Competed Under SAP(G)18$3.4M1.1%
Competed Under SAP(F)16$2.1M0.66%
G(NOT COMPETED UNDER SAP)4$395K0.12%
F(COMPETED UNDER SAP)8$283K0.090%
Other reported values2$27K0.0083%

Fair-opportunity and limited-source reporting

Reported valueAwardsPositive obligationsShare
Not reported63$320.9M100.0%

Other-than-full-and-open reasons

Reported valueAwardsPositive obligationsShare
Only One Source-Other (FAR 6.302-1 Other)(ONE)11$27.4M8.5%
SAP Non-Competition (FAR 13)(SP2)19$3.8M1.2%
Authorized by Statute (FAR 6.302-5(A)(2)(I))(OTH)2$26K0.010%
Less Than or Equal to the Micro-Purchase Threshold(MPT)1$7580%
Not reported30$289.8M90.3%

Contract pricing types

Reported valueAwardsPositive obligationsShare
Cost Plus Fixed Fee(U)2$251.6M78.4%
Firm Fixed Price(J)47$68.6M21.4%
J(FIRM FIXED PRICE)14$705K0.22%

Product or Service Codes

Reported valueAwardsPositive obligationsShare
Health R&d Services; Health Care - Other; Applied Research(AN42)1$225.0M70.1%
Medical and Surgical Instruments, Equipment, and Supplies(6515)1$52.8M16.4%
Medical- Other(Q999)1$26.6M8.3%
Drugs and Biologicals(6505)25$11.9M3.7%
in Vitro Diagnostic Substances, Reagents, Test Kits and Sets(6550)15$1.9M0.58%
Laboratory Equipment and Supplies(6640)11$1.3M0.41%
Other reported values9$1.4M0.45%

Awarding subagencies

Reported valueAwardsPositive obligationsShare
Office of Assistant Secretary for Preparedness and Response(7505)7$314.0M97.8%
National Institutes of Health(7529)46$6.3M1.9%
Food and Drug Administration(7524)4$357K0.11%
Centers for Disease Control and Prevention(7523)4$266K0.080%
Departmental Offices(1406)2$87K0.030%

Awarding offices

Reported valueAwardsPositive obligationsShare
Barda - Aspr / Daappo / Barda Dcma(75A501)6$261.2M81.4%
Aspr/Orm-Sns(75A503)1$52.8M16.4%
National Institutes of Health Olao(75N980)25$3.5M1.1%
National Institutes of Health Nhlbi(75N920)3$1.0M0.32%
National Institutes of Health - Cc(75N900)2$830K0.26%
National Institutes of Health Niaid(75N930)5$606K0.19%
Other reported values21$1.0M0.32%

Reported parent IDVs

Reported valueAwardsPositive obligationsShare
75A50123D00003(7505)1$225.0M70.1%
75A50122D00004(7505)4$9.6M3.0%
75N90023D00015(7529)2$1.9M0.59%
75N90023D00008(7529)1$330K0.10%
75F40125D00013(7524)1$15K0%
75N98025A00013(7529)1$11K0%
Not reported53$84.1M26.2%

Offers, award size, and timing

Median reported offers
1 median
54 reported · 9 not reported
Positive award obligations
$51K median
$20K–$249K middle 50%
Reported performance period
364 days (~12 months) median
63 reported · 0 not reported

Calculations group latest-period actions by award, retain awards with positive net obligations for share denominators, and use each award's latest reported USAspending procurement fields as of Sep 10, 2026. Blank competition, pricing, PSC, or parent-IDV values remain not reported; they are not inferred. Offer counts must be positive and below the FPDS 999 placeholder. Awarding organizations can differ from the funding agency that defines this page.

Top federal contractors

Latest 12-month market share, concentration, and complete prime contractor rankings across the period shown.

Prime contractor concentration
2 of 43prime contractors account for at least 80% of positive obligations in the last 12 months
Largest prime contractor
73.5%of positive obligations in the last 12 months
Leading four prime contractors
97.8%of positive obligations in the last 12 months
Leading eight prime contractors
99.0%of positive obligations in the last 12 months

Based on $306.0M in positive obligations during the 12 months ending Sep 10, 2026. Individual shares and movement appear in the searchable rankings below. Movement compares with Sep 11, 2024–Sep 10, 2025.

Last 12mo obligation volume: Highest positive obligations first; net deobligations follow by magnitude; contractors with no activity in the last 12 months follow by all-period obligations. Ranks use the complete contractor list and remain fixed when search narrows the results.

15 leading contractors
  1. #1

    Last 12mo obligations

    $225.0M

    73.5%

    Dollar movement

    −$114.5M

    vs. prior 12 months

    Last 12mo awards

    9 awards

    20 actions

    Historical and award details for ADVANCED TECHNOLOGY INTERNATIONAL
    Obligations: prior → latest
    $339.5M → $225.0M
    −33.7%
    Share: prior → latest
    77.1% → 73.5%
    −3.6 percentage points
    All-period obligations
    $911.5M
    50.0% of all-period positive obligations · 9 awards
    Recorded activity
    Since Dec 12, 2023
    through Aug 19, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside00
    Not reported99
    Reported small business00
    All-period set-aside types

    None reported.

  2. #2

    Last 12mo obligations

    $52.8M

    17.3%

    Dollar movement

    −$3.0M

    vs. prior 12 months

    Last 12mo awards

    1 award

    1 action

    Historical and award details for EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC.
    Obligations: prior → latest
    $55.7M → $52.8M
    −5.3%
    Share: prior → latest
    12.7% → 17.3%
    +4.6 percentage points
    All-period obligations
    $328.4M
    18.0% of all-period positive obligations · 1 award
    Recorded activity
    Since Oct 25, 2021
    through Jun 26, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside11
    Not reported00
    Reported small business00
    All-period set-aside types

    None reported.

  3. #3

    Last 12mo obligations

    $12.0M

    3.9%

    Dollar movement

    −$13.7M

    vs. prior 12 months

    Last 12mo awards

    2 awards

    3 actions

    Historical and award details for SANOFI VACCINES US INC.
    Obligations: prior → latest
    $25.8M → $12.0M
    −53.3%
    Share: prior → latest
    5.8% → 3.9%
    −1.9 percentage points
    All-period obligations
    $39.6M
    2.2% of all-period positive obligations · 46 awards
    Recorded activity
    Since Oct 27, 2021
    through Apr 8, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside22
    Not reported05
    Reported small business00
    All-period set-aside types

    None reported.

  4. #4

    Last 12mo obligations

    $9.6M

    3.1%

    Dollar movement

    +$1.9M

    vs. prior 12 months

    Last 12mo awards

    5 awards

    9 actions

    Historical and award details for SEQIRUS INC
    Obligations: prior → latest
    $7.7M → $9.6M
    +25.0%
    Share: prior → latest
    1.7% → 3.1%
    +1.4 percentage points
    All-period obligations
    $89.3M
    4.9% of all-period positive obligations · 27 awards
    Recorded activity
    Since Feb 22, 2022
    through May 8, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside00
    Not reported510
    Reported small business00
    All-period set-aside types

    None reported.

  5. #5

    Last 12mo obligations

    $1.7M

    0.54%

    Dollar movement

    +$1.6M

    vs. prior 12 months

    Last 12mo awards

    3 awards

    5 actions

    Historical and award details for MILTENYI BIOTEC, INC.
    Obligations: prior → latest
    $21K → $1.7M
    +7824.1%
    Share: prior → latest
    0% → 0.54%
    +0.5 percentage points
    All-period obligations
    $2.4M
    0.13% of all-period positive obligations · 5 awards
    Recorded activity
    Since Jun 29, 2022
    through Aug 6, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside01
    Not reported30
    Reported small business00
    All-period set-aside types

    None reported.

  6. #6

    Last 12mo obligations

    $653K

    0.21%

    Dollar movement

    −$151K

    vs. prior 12 months

    Last 12mo awards

    2 awards

    2 actions

    Historical and award details for VECTOR BIOMED INC.
    Obligations: prior → latest
    $804K → $653K
    −18.7%
    Share: prior → latest
    0.18% → 0.21%
    0.0 percentage points
    All-period obligations
    $2.1M
    0.11% of all-period positive obligations · 3 awards
    Recorded activity
    Since Aug 29, 2024
    through Jun 23, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside21
    Not reported00
    Reported small business21
    All-period set-aside types

    None reported.

  7. #7

    Last 12mo obligations

    $623K

    0.20%

    Dollar movement

    +$417K

    vs. prior 12 months

    Last 12mo awards

    7 awards

    7 actions

    Historical and award details for 10X GENOMICS, INC.
    Obligations: prior → latest
    $206K → $623K
    +202.6%
    Share: prior → latest
    0.050% → 0.20%
    +0.1 percentage points
    All-period obligations
    $6.1M
    0.34% of all-period positive obligations · 151 awards
    Recorded activity
    Since Nov 22, 2021
    through Mar 6, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside31
    Reported no set-aside45
    Not reported00
    Reported small business31
    All-period set-aside types
    • 88 · Total small business
  8. #8

    Last 12mo obligations

    $538K

    0.18%

    Dollar movement

    −$1.5M

    vs. prior 12 months

    Last 12mo awards

    2 awards

    2 actions

    Historical and award details for SOMALOGIC OPERATING CO., INC
    Obligations: prior → latest
    $2.1M → $538K
    −73.8%
    Share: prior → latest
    0.47% → 0.18%
    −0.3 percentage points
    All-period obligations
    $4.1M
    0.22% of all-period positive obligations · 13 awards
    Recorded activity
    Since Jan 28, 2022
    through May 18, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside21
    Not reported00
    Reported small business11
    All-period set-aside types

    None reported.

  9. #9

    Last 12mo obligations

    $376K

    0.12%

    Dollar movement

    +$376K

    vs. prior 12 months

    Last 12mo awards

    1 award

    1 action

    Historical and award details for OXFORD NANOPORE TECHNOLOGIES INC
    Obligations: prior → latest
    $0 → $376K
    Not comparable
    Share: prior → latest
    0% → 0.12%
    +0.1 percentage points
    All-period obligations
    $494K
    0.030% of all-period positive obligations · 4 awards
    Recorded activity
    Since Jun 27, 2023
    through Sep 12, 2025

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside10
    Not reported00
    Reported small business00
    All-period set-aside types

    None reported.

  10. #10

    Last 12mo obligations

    $347K

    0.11%

    Dollar movement

    +$347K

    vs. prior 12 months

    Last 12mo awards

    2 awards

    2 actions

    Historical and award details for PACIFIC BIOSCIENCES OF CALIFORNIA, INC
    Obligations: prior → latest
    $0 → $347K
    Not comparable
    Share: prior → latest
    0% → 0.11%
    +0.1 percentage points
    All-period obligations
    $656K
    0.040% of all-period positive obligations · 18 awards
    Recorded activity
    Since Nov 5, 2021
    through Jul 7, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside23
    Not reported00
    Reported small business21
    All-period set-aside types
    • 2 · Total small business
  11. #11

    Last 12mo obligations

    $330K

    0.11%

    Dollar movement

    +$330K

    vs. prior 12 months

    Last 12mo awards

    1 award

    2 actions

    Historical and award details for HOLOGIC SALES AND SERVICE, LLC
    Obligations: prior → latest
    $0 → $330K
    Not comparable
    Share: prior → latest
    0% → 0.11%
    +0.1 percentage points
    All-period obligations
    $566K
    0.030% of all-period positive obligations · 2 awards
    Recorded activity
    Since Dec 7, 2022
    through Mar 2, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside00
    Not reported10
    Reported small business00
    All-period set-aside types

    None reported.

  12. #12

    Last 12mo obligations

    $250K

    0.080%

    Dollar movement

    $0

    no change vs. prior 12 months

    Last 12mo awards

    1 award

    2 actions

    Historical and award details for UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Obligations: prior → latest
    $250K → $250K
    +0.0%
    Share: prior → latest
    0.060% → 0.080%
    0.0 percentage points
    All-period obligations
    $1.2M
    0.070% of all-period positive obligations · 1 award
    Recorded activity
    Since Jun 28, 2022
    through Jul 8, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside11
    Not reported00
    Reported small business00
    All-period set-aside types

    None reported.

  13. #13

    Last 12mo obligations

    $249K

    0.080%

    Dollar movement

    −$1.3M

    vs. prior 12 months

    Last 12mo awards

    1 award

    1 action

    Historical and award details for JACKSON LABORATORY
    Obligations: prior → latest
    $1.5M → $249K
    −83.7%
    Share: prior → latest
    0.35% → 0.080%
    −0.3 percentage points
    All-period obligations
    $3.2M
    0.17% of all-period positive obligations · 5 awards
    Recorded activity
    Since Aug 31, 2022
    through Jul 1, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside11
    Not reported00
    Reported small business00
    All-period set-aside types

    None reported.

  14. #14

    Last 12mo obligations

    $207K

    0.070%

    Dollar movement

    +$148K

    vs. prior 12 months

    Last 12mo awards

    1 award

    1 action

    Historical and award details for OLINK PROTEOMICS INC
    Obligations: prior → latest
    $59K → $207K
    +252.2%
    Share: prior → latest
    0.010% → 0.070%
    +0.1 percentage points
    All-period obligations
    $552K
    0.030% of all-period positive obligations · 7 awards
    Recorded activity
    Since Sep 13, 2023
    through Jun 1, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside13
    Not reported00
    Reported small business02
    All-period set-aside types

    None reported.

  15. #15

    Last 12mo obligations

    $175K

    0.060%

    Dollar movement

    +$175K

    vs. prior 12 months

    Last 12mo awards

    1 award

    1 action

    Historical and award details for REPLIGEN CORPORATION
    Obligations: prior → latest
    $0 → $175K
    Not comparable
    Share: prior → latest
    0% → 0.060%
    +0.1 percentage points
    All-period obligations
    $175K
    0.010% of all-period positive obligations · 1 award
    Recorded activity
    Since May 28, 2026
    through May 28, 2026

    Award reporting

    Latest and prior 12-month award reporting
    Reported award evidenceLatestPrior
    Reported set-aside00
    Reported no set-aside10
    Not reported00
    Reported small business10
    All-period set-aside types

    None reported.

Potential federal contract recompetes

Investigate potential recompetes surfaced by near-term end dates, award value, and recent contract changes.

ADVANCED TECHNOLOGY INTERNATIONAL

OT: THE PURPOSE OF THIS MODIFICATION IS TO ADMINISTRATIVELY UPDATE ATTACHMENT 1, SECTION 7. TASK ORDER POINTS OF CONTACT

$248.5M is obligated on an award with a reported potential end date of September 29, 2027.

Performance period

65.0%

As of Sep 10, 2026Potential end Sep 29, 2027

Current award value as a share of potential value

100.0%

$248.5M current$248.5M potential
Supporting data

Reported performance starts Sep 27, 2024.

No later potential end date is reported; current and potential end dates are both Sep 29, 2027.

$248.5M is obligated against $248.5M in current reported award value (100.0%).

Obligations are compared with current reported award value, not treated as a contract ceiling.

PIID 75A50424F64001

CANGENE CORPORATION

ADD FUNDING.

$510.9M is obligated on an award with a reported potential end date of December 31, 2027.

Performance period

94.0%

As of Sep 10, 2026Potential end Dec 31, 2027

Current award value as a share of potential value

86.0%

$510.9M current$594.2M potential
Supporting data

Reported performance starts May 30, 2006.

No later potential end date is reported; current and potential end dates are both Dec 31, 2027.

$510.9M is obligated against $510.9M in current reported award value (100.0%).

Obligations are compared with current reported award value, not treated as a contract ceiling.

PIID HHSO100200600017C

SANOFI VACCINES US INC.

THE PURPOSE OF THIS MODIFICATION: 1) TO REPLACE KRISTIN KELLY WITH SARAH HUMPHREY AS PRINCIPAL INVESTIGATOR ON THE CONTRACT (SEE FOLLOW-ON PAGE). 2) ALL OTHER TERMS AND CONDITIONS REMAIN THE SAME AND IN FULL FORCE AND EFFECT.

$53.2M is obligated on an award with a reported potential end date of January 31, 2028.

Performance period

53.6%

As of Sep 10, 2026Potential end Jan 31, 2028

Current award value as a share of potential value

66.6%

$53.2M current$79.8M potential
Supporting data

Reported performance starts Feb 1, 2025.

Current performance is reported through Jan 31, 2027.

$53.2M is obligated against $53.2M in current reported award value (100.0%).

Obligations are compared with current reported award value, not treated as a contract ceiling.

PIID 75A50125C00002

These are research leads, not confirmed recompetes. USAspending records through Sep 10, 2026; reported dates and values can change through later modifications.

Recent federal contract award activity

Recent contract actions with unusually large obligation changes or meaningful shifts in contractor and funding-office activity.

Modification

This action

+$210.0M

ADVANCED TECHNOLOGY INTERNATIONAL

OFC ASST SEC FOR PREPARENESS RES

OTA: THE PURPOSE OF THIS MODIFICATION IS TO INCREASE THE TOTAL ESTIMATED COST AND ADD FUNDING.

Why it stands out

One action equaled at least half of the market’s latest 12-month positive obligations.

The $210.0M action represented 68.6% of the market’s positive obligations over the latest 12 months.

Award net obligations
$304.0M
Share of 12-month positive obligations
68.6%
Supporting data
Prime contractor
#1 · 73.5% share
$114.5M net decline despite this positive action
Funding office
#1 · 81.0% attributed share
+81.0 percentage points · $332.4M net increase; action accounted for 63.2%
Related:Unusually large action
PIID 75A50124F61002 · Mod P00009
Deobligation

This action

−$14.6M

SANOFI VACCINES US INC.

BARDA - ASPR / DAAPPO / BARDA DCMA

NO-COST SUPPLEMENTAL AGREEMENT TO INCORPORATE BY EXECUTIVE ORDER 14042 - FAR DEVIATION CLAUSE 52.223-99, ENSURING ADEQUATE COVID SAFETY PROTOCOLS FOR FEDERAL CONTRACTORS. NO OTHER CHANGES APPLY.

Why it stands out

This award recorded a material contraction.

The action removed $14.6M. A deobligation does not by itself show lower requirement demand.

Award net obligations
$18.8M
Share of 12-month positive obligations
4.8%
Supporting data
Prime contractor
#3 · 3.9% share
−1.9 percentage points · $13.7M net decline; action exceeded it by $851K
Funding office
0% attributed share
−3.7 percentage points · $22.1M net decline; action accounted for 65.9%
PIID HHSO100201600039C · Mod P00008
Modification

This action

+$52.8M

EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC.

ASPR/ORM-SNS

ACAM2000, SMALLPOX (VACCINIA) VACCINE, LIVE (ACAM)

Why it stands out

This award grew while spending attributed to its office declined.

The modification added $52.8M while office-attributed obligations fell $3.0M overall.

Award net obligations
$857.6M
Share of 12-month positive obligations
17.3%
Supporting data
Prime contractor
#2 · 17.3% share
$3.0M net decline despite this positive action
Funding office
#2 · 17.0% attributed share
$3.0M net decline despite this positive action
PIID 75A50119C00071 · Mod P00015
Modification

This action

+$8.4M

SEQIRUS INC

BARDA - ASPR / DAAPPO / BARDA DCMA

THE PURPOSE OF THIS TASK ORDER IS TO PROCURE SERVICES FOR STORAGE AND STABILITY VACCINE BULK LOTS FROM PRIOR CONTRACTS FOR DEPARTMENT OF HEALTH AND HUMAN SERVICES UNDER IDIQ CONTRACT #75A50122D00004.

Why it stands out

This award grew while spending attributed to its office declined.

The modification added $8.4M while office-attributed obligations fell $22.1M overall.

Award net obligations
$23.3M
Share of 12-month positive obligations
2.8%
Supporting data
Prime contractor
#4 · 3.1% share
+1.4 percentage points · $1.9M net increase; action exceeded it by $6.5M
Funding office
0% attributed share
$22.1M net decline despite this positive action
PIID 75A50124F61008 · Mod P00008
Deobligation

This action

−$1.5M

GLAXOSMITHKLINE, LLC

BARDA - ASPR / DAAPPO / BARDA DCMA

THE PURPOSE OF THIS MODIFICATION IS TO: 1. EXERCISE FAR 52.217-8, OPTION TO EXTEND SERVICES FOR SIX (6) MONTHS. 2. AS RESULT OF THIS MODIFICATION, THE PERIOD OF PERFORMANCE FOR THE OPTION PERIOD 2 IS HEREBY CHANGED FROM 08/22/2020 - 08/21/2021 TO

Why it stands out

This award recorded a material contraction.

The action removed $1.5M. A deobligation does not by itself show lower requirement demand.

Award net obligations
$4.9M
Share of 12-month positive obligations
0.50%
Supporting data
Prime contractor
0% share
$2.2M net decline; action accounted for 70.3%
PIID 75A50119F33008 · Mod P00011
Base award

This action

+$1.0M

MILTENYI BIOTEC, INC.

NATIONAL INSTITUTES OF HEALTH OLAO

ADDING LINE ITEM 9: OPTION YEAR THREE (3) POP 03/13/2026-09/30/2026

Why it stands out

The contractor climbed 60 positions in this market.

It now ranks #5 by positive obligations over the latest 12 months.

Award net obligations
$1.4M
Share of 12-month positive obligations
0.33%
Supporting data
Prime contractor
#5 · 0.54% share
up 60 ranks · +0.5 percentage points · $1.6M net increase; action accounted for 61.1%
Funding office
#3 · 0.71% attributed share
+0.7 percentage points · $2.2M net increase; action accounted for 45.1%
PIID 75N98026F00003
View recent award activity by date (10)
  1. PROTEIN SCIENCES CORPDeobligation · PIID HHSO100200900106C
    Action−$192K
    Award net obligations$146.7M
  2. REVVITY HEALTH SCIENCES, INC.Deobligation · PIID 75N95021P00338
    Action−$3K
    Award net obligations$241K
  3. BECTON, DICKINSON AND CODeobligation · PIID 75N93021P01211
    Action−$159
    Award net obligations$17K
  4. BIO-TECHNE SALES CORPORATIONBase award · PIID 75N98026P01528
    Action+$34K
    Award net obligations$34K
  5. MIMETAS OPERATIONS US, CO.Deobligation · PIID 75N95021P00651
    Action−$23K
    Award net obligations$0
  6. LIFE TECHNOLOGIES CORPORATIONDeobligation · PIID 75N95021P00697
    Action−$30
    Award net obligations$22K
  7. GEMINI BIOPRODUCTS LLCDeobligation · PIID 75N93021P00125
    Action−$160
    Award net obligations$25K
  8. ARCHERDX LLCDeobligation · PIID 75N93021P01397
    Action−$16K
    Award net obligations$0
  9. BIOMERIEUX INCDeobligation · PIID 75N93021P01186
    Action−$2K
    Award net obligations$10K
  10. LIFE TECHNOLOGIES CORPORATIONBase award · PIID 75N98026P01509
    Action+$24K
    Award net obligations$24K

HHS biological product (except diagnostic) manufacturing market FAQs

Answers based on reported federal contract data.

Who are the top HHS biological product (except diagnostic) manufacturing contractors?

In the 12 months through September 10, 2026, ADVANCED TECHNOLOGY INTERNATIONAL, EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC., and SANOFI VACCINES US INC. were the leading HHS biological product (except diagnostic) manufacturing prime contractors by positive obligations.

  1. #1

    ADVANCED TECHNOLOGY INTERNATIONAL

    $224,999,997 in positive obligations

  2. #2

    EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC.

    $52,780,490 in positive obligations

  3. #3

    SANOFI VACCINES US INC.

    $12,027,150 in positive obligations

Rankings use reported USAspending award data.

Did HHS contract obligations decrease in the biological product (except diagnostic) manufacturing market?

Yes. Measured by net prime contract obligations, reported HHS activity in the biological product (except diagnostic) manufacturing market decreased 1% from $306,035,803 in the preceding 12 months to $303,022,669 in the 12 months through September 10, 2026.

Latest 12 months
$303,022,669
Net prime contract obligations
Preceding 12 months
$306,035,803
Net prime contract obligations
Change
−1%
Between matched 12-month periods

Reported contract actions, not outlays or a forecast.

What recent HHS contract award activity was reported in the biological product (except diagnostic) manufacturing market?

Recent HHS contract award activity reported in the biological product (except diagnostic) manufacturing market included actions for ADVANCED TECHNOLOGY INTERNATIONAL, SANOFI VACCINES US INC., and EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. during the 12 months through September 10, 2026.

Action obligations are transaction-level amounts, not current award-level obligations.

Which procurement methods were reported for HHS contracts under NAICS 325414?

From September 11, 2025 through September 10, 2026, HHS reported 63 positive-obligation awards for biological product (except diagnostic) manufacturing under NAICS 325414. The leading award type was delivery order. The leading reported procedure was negotiated proposal/quote.

Positive-obligation awards
63
Leading reported procedure
Negotiated Proposal/Quote
89.5% of positive obligations
Leading award type
Delivery Order
73.8% of positive obligations
Full and open
89.5%
of positive obligations
Reported parent IDV
73.8%
of positive obligations

Percentages use positive obligations as the denominator.

Which HHS biological product (except diagnostic) manufacturing awards may warrant recompete research?

3 HHS biological product (except diagnostic) manufacturing awards may warrant recompete research based on reported potential-end dates, including awards held by ADVANCED TECHNOLOGY INTERNATIONAL, CANGENE CORPORATION, and SANOFI VACCINES US INC.

Research leads, not confirmed recompetes. Dates may change through later modifications.

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Related market research

Complete market indexes:

Same NAICS at other agencies:

Nearby NAICS at this agency:

Markets sharing leading prime records:

Leading-prime vehicle memberships:

Company memberships do not establish award-channel use.

Reported obligations include contract actions from October 1, 2021 through September 10, 2026. Set-aside and business-size fields reflect award records, not a contractor's current eligibility.

Review data methodology